AKAP8 and breast cancer: Furthermore, intracellular phase-separated liquid-like structures regulate the localization and processing of mRNA.143,144 For example, AKAP95, a nuclear protein that participates in RNA splicing, generates liquid-like phase-separated condensates in vitro and in cells.145 AKAP95 is frequently overexpressed in human breast cancer, and the liquid condensates possess the abilities to support tumorigenesis with proper liquidity and dynamicity,145 which indicates that modifying the properties of biomolecular condensates can potentially target LLPS and provide useful ideas for cancer therapy.