dilncRNAs then attract the tumor suppressor P53-binding protein 1 (53BP1) to the DDR site and promote the formation of DNA damage repair foci via LLPS (Fig. 2 left).127 This method of repairing DNA double-strand breaks is very common in cancer cells and results in the avoidance of apoptosis.128. The gene discussed is TP53BP1; the disease is cancer.