According to our findings, PTPN11 expression was related in a positive way to the five MMR genes (EPCAM, MLH1, MSH2, MSH6, and PMS2) in 21 cancers, including BLCA, BRCA, CESC, COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, OV, PAAD, PCPG, PRAD, READ, STAD, THCA, THYM, and UCEC (Figure 8C). The gene discussed is MSH6; the disease is cancer.