Also, the correlation of PTPN11 expression with genetic mutation, protein phosphorylation, immune cell infiltration, tumor mutation burden (TMB), microsatellite instability (MSI), and mismatch repair genes (MMRs), as well as the underlying cellular pathway was identified, which suggests that PTPN11 may function as a potentially valuable marker for cancer treatment. The gene discussed is PTPN11; the disease is neoplasm.