PTPN11 and cancer: According to our findings, PTPN11 expression was related in a positive way to the five MMR genes (EPCAM, MLH1, MSH2, MSH6, and PMS2) in 21 cancers, including BLCA, BRCA, CESC, COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, OV, PAAD, PCPG, PRAD, READ, STAD, THCA, THYM, and UCEC (Figure 8C).