Our data revealed a more pronounced increase in CRP (48 (mg/dL) [6–104]), ALT (42.6 (U/L) [25.03–81.08]), AST (42 (U/L) [23.5–65.5]), creatinine (1 (mg/dL) [0.7–1.475]), urea (37.5 (mg/dL) [26–59]), ferritin (600 (ng/mL) [250–934]), LDH (357.5 (U/L) [245.5–484.5]), HR (90 (beats/min) [85–100]) and neutrophil % (73[57–85]) in group of patients with severe COVID-19 than patients with mild COVID-19 (p<0.05). This evidence concerns the gene GPT and COVID-19.