To compare the apoptotic effects of BDDD-721 and curcumin on medulloblastoma cells, DAOY and ONS-76 cells were incubated with 20 μM BDDD-721 and curcumin for 24 h, and the rate of apoptosis was further evaluated by Annexin V/PI assay. Here, ANXA5 is linked to medulloblastoma.