Potential biologic mechanisms underpinning relationships involving breast cancer outcomes, self-identified race and ethnicity, and interpersonal and structural racism could involve chronic psychosocial stress and genomic markers of inflammation (eg, DNA methylation or gene expression of interleukin receptors, C-reactive protein).43,44,45 Empirical studies designed explicitly to test whether stress and genomic inflammatory markers mediate associations between racism and breast cancer are lacking. This evidence concerns the gene CRP and breast carcinoma.