PPARGC1A and breast cancer: This increase resulted from very dissimilar grounds such as blocking mitophagy (VCR and Mdivi1), increased mitochondrial biogenesis (VPA), and even increased MM by DCA probably owing to targeting PGC1α as off-target, apart from its main action increasing PDH activity (we provide the analysis of a microarray dataset of BC-K562 cells treated with 1 mM VPA that was available from GEO database in Supp.