RAD51C and breast carcinoma: The breast cancer suppressor BRCA2 and the RAD51 paralog complexes, either RAD51B–RAD51C–RAD51D–XRCC2 (BCDX2) or RAD51C–XRCC3 (CX3) then help load RAD51 on the resected DNA to form a filament, displacing RPA.