For KIRC, a negative interrelation was confirmed between PRKDC gene and tumor purity (R = −0.105, P = 2.41e-2), but PRKDC expression and B cells (R = 0.295, P = 1.15e-10), CD8+ T cells (R = 0.165, P = 5.26e-04), CD4+ T cells (R = 0.341, P = 5.47e-14), macrophages (R = 0.468, P =8.12e-26), neutrophils (R = 0.468, P = 2.56e-26), and DCs (R = 0.408, P = 1.16e-19) indicated a positive association. The gene discussed is CD4; the disease is neoplasm.