We also observed a positive association between PRKDC expression and MSI for GBM (P = .033), OV (P = .0018), LUSC (P = .0013), SARC (P = .007), and KIRC (P = .0048) but a negative correlation for prostate adenocarcinoma (P = 1.1e-05), SKCM (P = .009), THCA (P = .00015), HNSC (P = .0059), and lymphoid neoplasm diffuse large B-cell lymphoma (P = .00044) (Fig. 6C). Here, PRKDC is linked to diffuse large B-cell lymphoma.