TNF and coronary artery disorder: These compounds are reported to have antiinflammatory, hypolipidemic, and cardioprotective effects, indicating their potential use in the treatment of CAD.[45–50] Moreover, quercetin can reduce the transcriptional activity of nuclear factor kappa B (NF-κB), thereby decreasing the levels of inflammatory cytokines such as IL-1β, IL-10, and TNF-α, which may treat CAD via antiinflammatory effects.[51] Resveratrol increases nitric oxide (NO) production in endothelial cells, stimulates endothelial nitric oxide synthase (eNOS) activity, and prevents eNOS uncoupling by upregulating its expression.