ASPS is characterized by an unbalanced translocation that results from the fusion of the TFE3 gene at Xp11 to the ASPL gene at 17q25, resulting in fusion of the TFE3-ASPL gene.[20] Reverse transcription-polymerase chain reaction and FISH are tools available for identifying this translocation. This evidence concerns the gene ASPSCR1 and alveolar soft part sarcoma.