KEAP1 and acute respiratory distress syndrome: Although we had preliminarily investigated the role and potential underlying mechanisms by which sevoflurane exerted its protective effects on LPS-induced ALI, the deep mechanisms by which sevoflurane inhibited LPS-induced oxidative stress through regulating other signaling pathways in addition to the Keap1/Nrf2 pathway was not fully understood, which needed to be further studied in our future research.