In this study, we postulated that PM augments the phenotypes of allergic asthma upon exposure to low‐dose Dp, and immune responses such as ILC2, Th2 cells, Th17 cells, IL13+ or IL‐5+ population from IL17+ CD4+ cells were all increased; however, inhibition of IL‐23 can reduce these phenotypes and immunologic changes. The gene discussed is CD4; the disease is allergic asthma.