CD8A and cancer: However, Cluster A is not less abundant in myeloid cells than Cluster B & C. This can further illustrate that myeloid cells play a “two‐sided” role, and cluster A has a stronger tendency to promote cancer progression.Cluster B has the highest immune score, and relatively more infiltration abundance of CD8+ T cells and cytotoxic lymphocytes (CTLs) tends to signify a more active immune microenvironment.