Similar findings were reported in a study of 116 patients from Brazil with T2D and hypertension, which showed a correlation between serum vitamin D levels and SBP.31 Moreover, recent studies in diabetics adults with hypothyroidism found that deficient vitamin D status were correlated with increased SBP.25 These results could be explained by the antihypertensive effect of vitamin D related to Renin-Angiotensin-Aldosterone System.32 The gene discussed is REN; the disease is hypertensive disorder.