CX3CL1 and neoplasm: For example, a recent microarray-based study on the effect of low-intensity resistance training on human subjects showed that the accurate mode and extent of exercise resulted in the upregulation of microRNAs, such as miR-630 and miR-5703, and myokines (fractalkine/CX3CL1) among 42 pathways and 12 cytokines/myokines, which subsequently suppressed tumor growth by inducing tumor-specific cytotoxic T cells (Hashida et al., 2021).