Along with IL-6, granulocyte-macrophage colony-stimulating factor (GM-CSF), G-CSF, and M-CSF are also produced by the same tumor cell for the expansion of some immune cells such as tumor-associated macrophages (TAMs), tumor-associated neutrophils (TANs), myeloid-derived suppressor cells (MDSCs), and dendritic cells (DCs). The gene discussed is CSF2; the disease is neoplasm.