ESR1 and premenstrual tension: Through the target intersection of active ingredients and diseases of PMS/PMDD, we obtained CHRM1/CHRM2/CHRM3/CHRM4/CHRM5, SLC6A2/SLC6A3/SLC6A4, ADRA1A/ADRA1B/ADRA1D/ADRA2A/ADRA2B/ADRA2C, ESR1/ESR2, and DRD1/DRD2 and other 26 intersection targets, mainly belonging to solute carrier family 6, cholinergic receptor, adrenergic receptor, estrogen receptor, and dopamine receptor families (Supplementary Table S6).