Recently, it is reported that CEP could suppress herpes simplex virus 1 by enhancing interferon-independent autophagy and counteract human cervical cancer via increasing autophagic influx (Law et al., 2014; Liu et al., 2021), and it has been demonstrated that inhibition of NF-κB could alleviate the reduction of autophagy and the MAPK pathway could inhibit autophagy by activating mTOR, a negative regulator in the process of autophagy (Chen et al., 2020; Duan et al., 2020). The gene discussed is NFKB1; the disease is cervical carcinoma.