Based on flow cytometric analyses of markers associated with activation (CD66b and CD62L shedding), immaturity (CD33), and maturity (CD15 and CD16), LDNs from active TB patients expressed higher levels of CD15, CD33, CD66b, CD16, and lower levels of CD62L compared to autologous NDNs (Deng et al., 2016; La Manna et al., 2019). The gene discussed is FCGR3B; the disease is tuberculosis.