IGF1 and acne: Interestingly, milk consumption appears to be associated with increased IGF1 levels in serum, consistent with previous reports in which IGF1 was positively associated with acne severity in adults (Norat et al., 2007; Roengritthidet et al., 2021) Our study suggests that diets with high IGF1 should be seriously considered during the outbreak of acne due to their direct effect on FA composition of facial sebum, especially for male acne patients.