ALDOA and renal carcinoma: Moreover, previous studies had shown that dysregulation of Wnt expression could lead to a variety of developmental abnormalities and human diseases, such as congenital kidney and urinary tract abnormalities, gallbladder kidney cancer, and renal cancer, among which fructose-bisphosphate aldolase A may induce cell proliferation and metastasis through Wnt/β-catenin signaling pathway [32, 33].