According to their normalized enrichment score (NES) and false discovery rate (FDR) q value (FDR <0.05), eight signal transduction pathways were identified and selected, which were cell cycle, DNA replication, insulin signaling pathway, natural killer cell-mediated cytotoxicity, MTOR signaling pathway, primary immunodeficiency, WNT signaling pathway, and TGF beta signaling pathway (Figure 6 and Table 3). This evidence concerns the gene INS and inborn error of immunity.