As shown in Figure 1, serum afamin quartiles were positively associated with the prevalence of NAFLD (P < 0.001) and were overweight (P = 0.002), while there was no significant association between the serum afamin quartiles and the prevalence of T2DM, dyslipidemia, or hypertension. The gene discussed is AFM; the disease is metabolic dysfunction-associated steatotic liver disease.