Significant predictors of HF events were IVS-QSb, IVS-QSt, Lat-QSb, Lat-QSt, SCD family history, 6-MWT, CREA, ApoA1, MB, RVD-1, RVD-2, LVEF, LAVI, P, QRS, and PR. The gene discussed is APOA1; the disease is hydrops fetalis.