The results showed that they were significantly enriched in multiple pathways such as Inflammatory response, interferon-alpha response, interferon-gamma response, TNF signaling via NF-kB, allograft rejection, and pi3k Akt mTOR signaling, but also in various cardiomyopathies such as dilated cardiomyopathy and hypertrophic cardiomyopathy. The gene discussed is TNF; the disease is dilated cardiomyopathy.