As a consequence, combining the detection of Mycoplasma pneumoniae-specific antibody, C-reactive protein, and procalcitonin in the diagnosis of children with Mycoplasma pneumoniae pneumonia has a higher clinical application value than single item detection, which can provide a reliable reference basis for clinical practice and aid in evaluating the recovery effect of children, and is worthy of application. Here, CRP is linked to Mycoplasma pneumoniae pneumonia.