Specifically, the overexpression of BAMBI, BRD9, CCT3, CDC123, DEGS1, DENR, DHX37, EIF3B, GAPDH, HM13, HSP90AA1, IQCA1, LRP4, MCM8, PIGU, PPFIA4, PPM1G, RRP7A, SEC61A1, SLC25A39, SLC41A3, SOX11, SPC25, TAGLN2, ZC3H3, and ZNF207 was significantly associated with a poor prognosis for patients with HCC (Figures 5 and S3). Here, SPC25 is linked to hepatocellular carcinoma.