MIF and myocardial infarction: MI reduced EF in female mice at day 1 (29.99 ± 1.37 MIF and 30.22 ± 2.47 SMIF) with no further significant decrease at day 7 nor with CS (25.69 ± 2.07 MIF and 24.29 ± 2.84 SMIF) (Fig. 3A); however, both female groups showed moderate and equivalent increases from day 1 in LVESV (3.01 ± 0.10 to 3.90 ± 0.22 MIF and 2.88 ± 0.12 to 3.84 ± 0.30 SMIF) and LVEDV (4.31 ± 0.11 to 5.24 ± 0.23 MIF and 4.13 ± 0.05 to 5.03 ± 0.23 SMIF) at day 7 post-MI, with LV adverse remodeling in progress through 7 days (Figs. 2 and 3).