Following univariate analysis, 27 variables (P < 0.2) entered into the multivariable analysis: sex (male), BMI, LoHS, DBP, anemia, RBC, neutrophil, lymphocyte, platelet, TC, LDL-C, creatinine, BUN, AST, ALT, cTnI/T, BNP (NT-proBNP), QRS fraction, pulmonary congestion (X-ray), LVEF, LAD, ACEI/ARB, β-blocker, Tolvaptan, recombinant human brain natriuretic peptide (rhBNP), calcium channel blockers, and Statin. The gene discussed is NPPB; the disease is anemia.