LRFN1 and cancer: Prognostic implication of LRFN1 expression among pan-cancers from TCGA database using log rank test [− log10(P-value)] was shown in Fig. 3D. LRFN1 expression showed the strongest association with prognosis of ccRCC patients (Zscore = 6.484), and significantly predicts prognosis for patients with COAD, KIRP, PRAD, SKCM, STAD and THCA.