Interestingly, after reviewing the association between LRFN1 expression and immune cells infiltration levels in pan-cancer, we found that LRFN1 was highly consistent with the infiltration of tumor immune-infiltrating lymphocytes, but this finding was only present in RCC (including three different subtypes) instead of other cancers (Fig. 5F). This evidence concerns the gene LRFN1 and renal cell carcinoma.