SYP and Sepsis: There were no significant changes in synaptophysin levels in any of the groups analyzed after the EE protocol in animals submitted to sepsis (sham + SE = 0.73 ± 0.11; sham + EE = 0.68 ± 0.14; CLP + SE = 0.68 ± 0.09; CLP + EE = 0.64 ± 0.08) (Fig. 10a).