LEP and obesity due to melanocortin 4 receptor deficiency: For instance, several DEMs in the present work, including miR-144-5p, miR-192, miR-320, miR-378, miR-122, miR-24-3p, miR-223-3p and miR-146-5p, have been found to have strong correlations with various obesity-related metabolic indices in blood, such as serum leptin and triglycerides60–64.