To gain further insight into the significance of TGFβ in diseases associated with inflammatory bone erosion, we analyzed the DEG profile by taking advantage of a recently published dataset60, in which the genome-wide gene expression of PBMCs from cross-sectional cohorts, including 82 SLE patients and 84 RA patients who routinely visited either Brigham and Women’s Hospital or Northwell Health during the same time period, was obtained. This evidence concerns the gene TGFB1 and rheumatoid arthritis.