ASXL1 and myeloproliferative disorder: Concurrent cytogenetic analysis revealed normal karyotypes.Six years after diagnosis, doubleframeshift mutations at two loci in ASXL1 (c.1934dup, p.Gly646TrpfsTer12 and c.2428_2431del, p.Asp810MetfsTer7) were found in one patient with PMF (family 2) during screeningfor MPN-related genes.