In stratified analyses, there was no association of factor 10 and NASH in carriers of the PNPLA3 Ile148Met variant (G allele) (OR [95% CI], 0.8 [0.5–1.4], P = 0.5), while participants without a copy of the variant showed an association (OR [95% CI], 0.3 [0.1–0.6], P = 7 × 10–4) (Supplemental Figure 1). This evidence concerns the gene PNPLA3 and metabolic dysfunction-associated steatohepatitis.