Similarly, downregulation of the lincRNAs MEG9 (maternally expressed 9), HULC (hepatocellular carcinoma upregulated long noncoding RNA), and MIAT (myocardial infarction associated transcript, also called GOMAFU) was reported by Fenoglio et al. who studied PBMC samples from 27 patients with RRMS, 13 patients with PPMS, and 31 healthy controls in the Italian population [19]. Here, MEG9 is linked to primary progressive multiple sclerosis.