The authors showed that by acting as a miR-221-3p sponge, MIAT can derepress its target TGFBR1 (TGFB receptor 1) and deregulate TGF-β1 (transforming growth factor) and Nrf2 (nuclear factor E2-related factor 2) expression to promote apoptosis, neuroinflammation, and oxidative stress in PD (Table S1). This evidence concerns the gene TGFB1 and Parkinson disease.