Increased production of proinflammatory cytokines also plays an important role in the pathogenesis of T2D, and contributes to long-term micro- and macrovascular complications.19,20 In the course of prediabetes, it is common for patients to have higher levels of inflammatory markers, such as IL-6 and TNF-α,21 observed in the current and in the previous study.12 In contrast, supplementation with Eriomin led to downregulation of low-grade inflammation in these patients, mainly due to reduced serum levels of these markers: IL-6 (−14%) and TNF-α (−20%). This evidence concerns the gene TNF and prediabetes syndrome.