Available literature suggests that the main presenting pathologies of wild‐type ATTR are cardiomyopathy, carpal tunnel syndrome, and spinal canal stenosis, while patients with hereditary ATTR present with a higher incidence of gait instability, gastrointestinal symptoms, urinary incontinence, and neuropathic pain14, 20, 21; clinical experience suggests that these differences in presenting pathologies are also found in different populations of Asian patients.22, 23, 24, 25. This evidence concerns the gene TTR and cardiomyopathy.