CX3CR1 and ischemic stroke: utilized ischemic stroke models with CX3CR1GFP/+CCR2RFP/+ bone marrow (BM) chimeric mice to study the effects of CCR2 and CX3CR1 on monocyte/macrophage recruitment following stroke and showed that non-classical, alternatively activated CX3CR1+ monocytes/macrophages were absent in the brain of CCR2 null mice.