Higher transitional MZ B cells in patients with CVID with autoimmune cytopeniaLower percentage of naive and non-class-switched memory B cells were seen in patients with CVID with autoimmunityPatients with CVID with multiple autoimmune syndromes had higher level of CD3+ T cells, CD4+ T cells and CD21low B cells and lower number of T regs and naïve B cell when compared with patients with CVID with one autoimmune syndrome. The gene discussed is CD4; the disease is common variable immunodeficiency.