F3 and Familial prostate cancer: Tissue factor is overexpressed in a variety of solid cancers, such as cervical cancer (Cocco et al., 2011), NSCLC (Koomägi and Volm, 1998), endometrial cancer (Fadare et al., 2011), prostate cancer (Akashi et al., 2003) and ovarian cancer (Abu Saadeh et al., 2013).