IL6 and coronary artery disorder: Subsequently, neutrophils secrete inflammatory mediators such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α), which attract smooth muscle cells and macrophages for phagocytosis, resulting in vascular endothelial dysfunction (19, 20), and anti-inflammatory medicine or cytokines can improved the vascular endothelial dysfunction and decreased the risk of CHD (21, 22).