TNF and Infertility: In our study, the mean Th1/Th2 (TNF-α/IL-4) ratio was 29.42 ± 12.90 in the treated group, which was much higher than the Th1/Th2 ratio of both infertile patients (2.4 ± 0.4, n = 80) [4] and patients with IVF failures (12.81 ± 2.52, n = 9) in other studies [10], suggesting a severer infertile condition in our population.