In the control and migraine group, CGRP-IH is associated with vmPCAtot responses (OR = 1.19; 95% CI 1.06-1.33; p = 0.003) and Et-CO2tot responses (OR = 1.31; 95% CI 1.08-1.59; p = 0.006) but not with MAPtot responses (OR = 0.97; 95% CI 0.94-1.01; p = 0.221) and HRtot responses (OR = 1.00; 95% CI 0.95-1.06; p = 0.784). This evidence concerns the gene CALCA and migraine disorder.