In addition, the top 15 pathways in which the core targets were enriched were identified (Figure 7), mainly including the neurotrophin signaling pathway, PI3K-Akt signaling pathway, cell cycle, apoptosis, viral carcinogenesis, prostate cancer, hepatitis C, pancreatic cancer, Epstein-Barr (EB) virus infection, human cytomegalovirus infection, proteoglycans in cancer, hepatitis B, chronic myeloid leukemia, Kaposi sarcoma-associated herpes, and microRNAs (miRNAs) in cancer. The gene discussed is BDNF; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.