Recent studies have shown that the expression of plasma BNP in patients with traumatic brain injury, etc. is significantly higher than that in healthy people, and the concentration of BNP is positively correlated with the amount of cerebral hemorrhage and the degree of cerebral edema, and also has a correlation with the degree of neurological deficit, suggesting that BNP is useful for the diagnosis and treatment of cerebrovascular diseases [13, 14]. This evidence concerns the gene NPPB and edema.