Furthermore, abnormal nuclear distribution of PCBP-1 participates in Huntington’s disease (HD) pathogenesis, suggesting that as RBPs, like PCBP-1, may contribute to the pathophysiological processes under neurodegenerative conditions (Geuens et al., 2017; Mori et al., 2019). The gene discussed is PCBP1; the disease is Huntington disease.