LYN is reported to be an essential regulator of immunoreceptor signalling that initiates both proinflammatory and suppressive signalling pathways in myeloid immune cells, including neutrophils, dendritic cells, monocytes, macrophages, and B lymphocytes (Brian and Freedman, 2021), whose deficiency leads to the development of autoimmune disease (Hibbs and Dunn, 1997). This evidence concerns the gene LYN and autoimmune disease.