PML and chronic myelogenous leukemia, BCR-ABL1 positive: The chromosome 9 and 22 translocations in chronic myelogenous leukemia (CML) produce the PML-RARα gene; similar chromosomal translocations in tumors are reported to produce fusion-circular RNAs (f-circRNAs) and facilitate the progression of diseases such as leukemia (37, 38).