Moreover, both 5 and 10 μM neferine memorably increased the relative protein expression of E-cadherin, while notably declined the relative protein level of N-cadherin and vimentin of IHH-4 and CAL-62 cells, suggesting that neferine overtly hindered the EMT of thyroid cancer cells (Figures 2(c)–2(e)). The gene discussed is CDH1; the disease is thyroid gland carcinoma.