Two cohorts (GSE17536 and GSE14333) (30, 31) containing 226 specimens at different stages of CRC proved that low LRRC19 expression was markedly related to poorer prognosis (OS HR = 0.84, 95% CI = 0.72 to 0.98, Cox P=0.025916; DFS HR = 0.75, 95% CI = 0.61 to 0.92, Cox P=0.005594; DSS HR = 0.80, 95% CI = 0.68 to 0.95, Cox P=0.011420; DFS HR = 0.78, 95% CI = 0.68 to 0.89, Cox P=0.000287) (Figures 5(c)–5(f)). Here, LRRC19 is linked to colorectal carcinoma.